Technical Excellence Across Microbial Kingdoms

Bacteria

Bacteria have long been used in industrial fermentation (e.g., E. coli, Bacillus subtilis), but challenges emerge when working beyond these model organisms. At Evologic, we specialize in the production and stabilization of difficult-to-produce bacteria – particularly relevant for the Agri-Tech market.

Key strengths:

Expertise in culturing non-model, fastidious Gram-negative strains
Design of custom fermentation media and process parameters to support strain-specific growth requirements
Downstream processing strategies to ensure long-term viability and shelf stability (Bioshield®)
Integration of formulation and drying technologies for robust, field-ready products

Fungi

Filamentous fungi, particularly those outside the industrial standards (e.g. Penicillium, Trichoderma, Aspergillus), are notoriously difficult to scale. The vast majority of fungi are still primarily cultivated through solid-state fermentation (SSF) that comes with inherent limitations in sterility, process control, and scalability. Additionally, SSF can be successfully used to cultivate only a miniscule fraction of the fungal kingdom – out of more than three million fungal species, only few species have been commercialized. It is time to remove the constraints to biological manufacturing and unlock the numerous solutions fungal kingdom is offering. Evologic is doing so by:

Introducing a proprietary: manufacturing technology that overcomes quality and scalability challenges of solid-state fermentation: Mycotec®
Engineering bioreactor environments for hyphae and spore formation without foam or clogging
Achieving contamination-free fungal spore production with consistent yields and performance
Targeting high-value applications such as biocontrol agents and novel agrochemical alternatives

Hairy Roots

Hairy root cultures are one of biotechnology’s most powerful but underutilized tools for producing plant-derived bioactive molecules. Generated through Agrobacterium rhizogenes-mediated transformation, these root systems are non-photosynthetic and source carbon from supplied media, enabling precise control over input and output. Our patented hairy root bioreactor technology enables: It is time to remove the constraints to biological manufacturing and unlock the numerous solutions fungal kingdom is offering. Evologic is doing so by:

Production of secondary plant metabolites (e.g., flavonoids, alkaloids, terpenoids) at commercial scale
Fully controlled, non-GMO bioprocesses that decouple supply from environmental and geopolitical variability
Process development and scale-up from bench to m³-scale bioreactors
Application in agriculture, cosmetics, and pharma where traceability, safety, and sustainability are non-negotiable

We’re proud to be a core partner in the EU Horizon 2020 InnCoCells project, developing safe and effective bioactive cosmetic ingredients from sustainable plant-based sources.

Featured in the Horizon 2020 InnCoCells Project.